P02.133. Randomized double blinded clinical trial of Ojeoksan products extracted through different methods for low back pain

Methods The study was approved by the Ethics Committee of Kyunghee Oriental Medical Center in Seoul, Korea. Sixty subjects (M:F=26:34) with low back pain were recruited in the study and randomly allocated to MIE group, ECD group and Placebo group. During 4 weeks, the MIE group took the Ojeoksan Mixture of Independently Extracted Herbs, the ECD group took the Ojeoksan Extract from combined Decoction, and the Placebo group took a placebo. The effect of Ojeoksan on pain was measured with VAS (Visual Analogue Scale) and SF-36 Bodily Pain scale. Disability was measured with RMDQ (Roland-Morris Disability Questionnaire). General health was measured with the SF-36 (36-Item Short-Form Quality of Life Questionnaire) and range of motion was measured with MMST (Modified-Modified Schober Test) at baseline, 2 weeks and 4 weeks. Efficacy was evaluated with the SPSS 12.0 paired t-test for intragroup testing and ANCOVA (Analysis of covariance) for intergroup testing.